Difference between revisions of "AMG-41"

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(Created page with "AMG-36 is an analgesic drug which is a cannabinoid agonist. It is a derivative of Δ8THC substituted with a cyclopentane group on the 3-position side chain. AMG-36 is...")
 
 
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AMG-36 is an analgesic drug which is a cannabinoid agonist. It is a derivative of Δ8[[THC]] substituted with a cyclopentane group on the 3-position side chain. [[AMG-36]] is a potent agonist at both [[CB1]] and [[CB2]] with moderate selectivity for CB1, with a Ki of 0.4nM at CB1 vs 1.9nM at CB2.
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'''AMG-41''' is an analgesic drug which is a cannabinoid agonist. It is a derivative of Δ8-[[THC]] substituted with a cyclopropyl group on the C1'-position of the C3-alkyl side chain. AMG-41 is a potent agonist at both [[CB1]] and [[CB2]], with a Ki of 0.4nM at CB1 vs 0.9nM at CB2.

Latest revision as of 19:13, 14 February 2015

AMG-41 is an analgesic drug which is a cannabinoid agonist. It is a derivative of Δ8-THC substituted with a cyclopropyl group on the C1'-position of the C3-alkyl side chain. AMG-41 is a potent agonist at both CB1 and CB2, with a Ki of 0.4nM at CB1 vs 0.9nM at CB2.