Adm1n: Created page with "'''AM-411''' is an analgesic drug that is a cannabinoid agonist. It is a derivative of Δ8THC substituted with an adamantyl group at the 3-position, demonstrating that the..."

2015-02-15T10:55:12Z

Created page with "'''AM-411''' is an analgesic drug that is a cannabinoid agonist. It is a derivative of Δ8THC substituted with an adamantyl group at the 3-position, demonstrating that the..."

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'''AM-411''' is an analgesic drug that is a cannabinoid agonist. It is a derivative of Δ8[[THC]] substituted with an adamantyl group at the 3-position, demonstrating that the binding pocket for the alkyl chain at this position can accommodate significant bulk.

AM-411 is a potent and fairly selective [[CB1]] full agonist with a Ki of 6.80nM, but is still also a moderately potent [[CB2]] agonist with a Ki of 52.0nM. It produces similar effects to other cannabinoid agonists such as analgesia, sedation, and anxiolysis.

==See also==

* [[AM-087]]
* [[AM-1248]]
* [[KM-233]]

AM-411 - Revision history

Adm1n: Created page with "'''AM-411''' is an analgesic drug that is a cannabinoid agonist. It is a derivative of Δ8THC substituted with an adamantyl group at the 3-position, demonstrating that the..."